Cells contain specialist proteins termed transporters (or solute carriers) which are responsible for the uptake of both nutrients and drug molecules into the cell. My research focuses on developing biochemical tools to understand transporters, in particular those associated with cancer progression (SLC7A11) and treatment (SLC46A1) as well as inflammation (SLC15A4). In addition, I am also involved in understanding the role of solute carriers in fungal glycosylation with the aim of targeting these for drug discovery.
I received my PhD from the University of St Andrews where I studied DNA recombination, in particular the mechanism of Holliday Junction resolving enzymes. Following this, I continued with researching into DNA repair mechanisms while working for Cancer Research UK at their Clare Hall research laboratories (now the Crick Institute). After this I made the switch to researching mechanisms of secondary active transport.
College
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Department
Department of Biochemistry
