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Changes in iPSC-Astrocyte Morphology Reflect Alzheimer's Disease Patient Clinical Markers

Rowland HA, Miller G, Liu Q, Li S, Sharp NR, Ng B, Wei T, Arunasalam K, Koychev I, Hedegaard A, Ribe EM, Chan D, Chessell T, Kocagoncu E, Lawson J, Malhotra P, Ridha BH, Rowe JB, Thomas AJ, Zamboni G, Zetterberg H, Cader MZ, Wade-Martins R, Lovestone S, Nevado-Holgado A, Kormilitzin A, Buckley NJ

December 2024 | Journal article | Stem Cells | Read


Safety and Efficacy of the Blood-Stage Malaria Vaccine RH5.1/Matrix-M in Burkina Faso: Interim Results of a Double-blind, Randomised, Controlled, Phase 2b Trial in Children

Natama HM, Salkeld J, Somé A, Soremekun S, Diallo S, Traoré O, Rouamba T, Ouédraogo F, Ouédraogo E, Daboné KCS, Koné NA, Compaoré ZMJ, Kafando M, Bonko MDA, Konaté F, Sorgho H, Nielsen CM, Pipini D, Diouf A, King LDW, Shaligram U, Long CA, Cho JS, Lawrie AM, Skinner K, Roberts R, Miura K, Bradley J, Silk SE, Draper SJ, Tinto H, Minassian AM

December 2024 | Journal article | The Lancet Infectious Diseases | Read


Unlocking Intracellular Protein Delivery by Harnessing Polymersomes Synthesized at Microliter Volumes using Photo-PISA

Thanapongpibul C, Rifaie-Graham O, Ojansivu M, Najer A, Kim H, Bakker SE, Chami M, Peeler DJ, Liu C, Yeow J, Stevens MM

December 2024 | Journal article | Advanced Materials | Read


Structure and Mechanism of the Zorya Anti-Phage Defense System

Hu H, Popp PF, Hughes TCD, Roa-Eguiara A, Rutbeek NR, Martin FJO, Hendriks IA, Payne LJ, Yan Y, Humolli D, Klein-Sousa V, Songailiene I, Wang Y, Nielsen ML, Berry RM, Harms A, Erhardt M, Jackson SA, Taylor NMI

December 2024 | Journal article | Nature | Read


Structural Insights into the High Basal Activity and Inverse Agonism of the Orphan Receptor GPR6 Implicated in Parkinson's Disease

Barekatain M, Johansson LC, Lam JH, Chang H, Sadybekov AV, Han GW, Russo J, Bliesath J, Brice NL, Carlton MBL, Saikatendu KS, Sun H, Murphy ST, Monenschein H, Schiffer HH, Popov P, Lutomski CA, Robinson CV, Liu ZJ, Hua T, Katritch V, Cherezov V

December 2024 | Journal article | Science Signaling | Read


Transfer Learning Bayesian Optimization for Competitor DNA Molecule Design for Use in Diagnostic Assays

Sedgwick R, Goertz JP, Stevens MM, Misener R, van der Wilk M

December 2024 | Journal article | Biotechnology and Bioengineering | Read


Investigating the Role of Elastin and Extracellular Matrix Damage in Cardiovascular Calcification

Radvar E, Mehta K, D'Ambrosio A, Mastroianni G, Al-Jawad M, Stevens MM, Mata A, Elsharkawy S

December 2024 | Journal article | Journal of Structural Biology | Read


Molecular Tags for Electron Cryo-Tomography

Silvester E, Baker LA

December 2024 | Journal article | Emerging Topics in Life Sciences | Read


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